Publications

Azcona JA, Wacker AS, Lee C-H, Fung EK, Jeitner TM, Manzo OL, Di Lorenzo A, Babich JW, Amor-Coarasa A, Kelly JM. 2-[18F]Fluoropropionic Acid PET Imaging of Doxorubicin-Induced Cardiotoxicity. Mol Imaging Biol. 2025;27(1):109-119.

de Lima RPereira, Li A, Gilani A, Rubio-Navarro A, Warren CD, Kong IY, Geri JB, Lo JC. C3aR1 on β cells Enhances β cell Function and Survival to Maintain Glucose Homeostasis. Mol Metab. 2025;:102134.

Naderi J, Johnson AKelsey, Thakkar H, Chandravanshi B, Ksiazek A, Anand A, Vincent V, Tran A, Kalimireddy A, Singh P, Sood A, Das A, Talbot CLamar, Distefano IA, J Maschek A, Cox J, Li Y, Summers SA, Atkinson DJ, Turapov T, Ratcliff JA, Fung J, Shabbir A, M Yassin S, Shiow S-AToh Ee, Holland WL, Pitt GS, Chaurasia B. Ceramide-induced FGF13 impairs systemic metabolic health. Cell Metab. 2025;.

Zhu J, Li Z, Xue D, Meng Z, Shao S, Pulecio J, Zhang G, Huangfu D, Evans T, Schultz PG, Chen S. A Chemical Epigenetic Probe to Capture the Site-Specific DNA-Binding Protein Complex. Res Sq. 2025;.

Homan EA, Gilani A, Rubio-Navarro A, Johnson MA, Schaepkens OM, Cortada E, de Lima RPereira, Stoll L, Lo JC. Complement 3a receptor 1 on macrophages and Kupffer cells is not required for the pathogenesis of metabolic dysfunction-associated steatotic liver disease. Elife. 2025;13.

Jin S, Yoon NAe, Wei M, Worgall T, Rubinelli L, Horvath TL, Min W, Diano N, Di Lorenzo A, Diano S. Endoplasmic reticulum Nogo drives AgRP neuronal activation and feeding behavior. Cell Metab. 2025;.

Lin S, Gade AR, Wang H-G, Niemeyer JE, Galante A, DiStefano I, Towers P, Nunez J, Matsui M, Schwartz TH, Rajadhyaksha A, Pitt GS. Interneuron FGF13 regulates seizure susceptibility via a sodium channel-independent mechanism. Elife. 2025;13.

Zhang F, Evans T. Stage-specific DNA methylation dynamics in mammalian heart development. Epigenomics. 2025;:1-13.

Rubinelli L, Manzo OLaura, Sungho J, Del Gaudio I, Bareja R, Marino A, Palikhe S, Di Mauro V, Bucci M, Falcone DJ, Elemento O, Ersoy B, Diano S, Sasset L, Di Lorenzo A. Suppression of endothelial ceramide de novo biosynthesis by Nogo-B contributes to cardiometabolic diseases. Nat Commun. 2025;16(1):1968.

Gilani A, Stoll L, Homan EA, Lo JC. Adipose Signals Regulating Distal Organ Health and Disease. Diabetes. 2024;73(2):169-177.

Ma L, Gilani A, Rubio-Navarro A, Cortada E, Li A, Reilly SM, Tang L, Lo JC. Adipsin and Adipocyte-derived C3aR1 Regulate Thermogenic Fat in a Sex-dependent Fashion. JCI Insight. 2024;.

Katchman AN, Zakharov SI, Bohnen MS, Jimenez ASanchez, Kushner JS, Yang L, Chen B-X, Nasari A, Liu G, Rabbani DE, Han J, Leu C-S, Pitt GS, Marx SO. Augmented Cardiac Inotropy by Phosphodiesterase Inhibition Requires Phosphorylation of Rad and Increased Calcium Current. Circulation. 2024;149(20):1617-1620.

Cortada E, Yao J, Xia Y, Dündar F, Zumbo P, Yang B, Rubio-Navarro A, Perder B, Qiu M, Pettinato AM, Homan EA, Stoll L, Betel D, Cao J, Lo JC. Cross-species single-cell RNA-seq analysis reveals disparate and conserved cardiac and extracardiac inflammatory responses upon heart injury. Commun Biol. 2024;7(1):1611.

Duca S, Xia Y, Elmagid LAbd, Bakis I, Qiu M, Cao Y, Guo Y, Eichenbaum JV, McCain ML, Kang J, Harrison MRM, Cao J. Differential vegfc expression dictates lymphatic response during zebrafish heart development and regeneration. Development. 2024;151(22).

Buth JE, Dyevich CE, Rubin A, Wang C, Gao L, Marks T, Harrison MRm, Kong JH, M Ross E, Novitch BG, Pearson CAlayne. Foxp1 suppresses cortical angiogenesis and attenuates HIF-1alpha signaling to promote neural progenitor cell maintenance. EMBO Rep. 2024;25(5):2202-2219.

Sam J, Torregroza I, Evans T. Gata6 functions in zebrafish endoderm to regulate late differentiating arterial pole cardiogenesis. Development. 2024;.

Southwell N, Manzo O, Bacman S, Zhao D, Sayles NM, Dash J, Fujita K, D'Aurelio M, Di Lorenzo A, Manfredi G, Kawamata H. High fat diet ameliorates mitochondrial cardiomyopathy in CHCHD10 mutant mice. EMBO Mol Med. 2024;.

Yang L, Han Y, Zhang T, Dong X, Ge J, Roy A, Zhu J, Lu T, J Vandana J, de Silva N, Robertson CC, Xiang JZ, Pan C, Sun Y, Que J, Evans T, Liu C, Wang W, Naji A, Parker SCJ, Schwartz RE, Chen S. Human vascularized macrophage-islet organoids to model immune-mediated pancreatic β cell pyroptosis upon viral infection. Cell Stem Cell. 2024;.

Papa A, Morfin PJDel Rive, Chen B-X, Yang L, Katchman AN, Zakharov SI, Liu G, Bohnen MS, Zheng V, Katz M, Subramaniam S, Hirsch JA, Weiss S, Dascal N, Karlin A, Pitt GS, Colecraft HM, Ben Johny M, Marx SO. A membrane-associated phosphoswitch in Rad controls adrenergic regulation of cardiac calcium channels. J Clin Invest. 2024;.

Timothy KW, Bauer R, Larkin KA, Walsh EP, Abrams DJ, Corcia CGonzalez, Valsamakis A, Pitt GS, Dick IE, Golden A. A Natural History Study of Timothy Syndrome. medRxiv. 2024;.

Timothy KW, Bauer R, Larkin KA, Walsh EP, Abrams DJ, Corcia CGonzalez, Valsamakis A, Pitt GS, Dick IE, Golden A. A Natural History Study of Timothy Syndrome. Orphanet J Rare Dis. 2024;19(1):433.

Manzo OLaura, Nour J, Sasset L, Marino A, Rubinelli L, Palikhe S, Smimmo M, Hu Y, Bucci MRosaria, Borczuk A, Elemento O, Freed JK, Norata GDanilo, Di Lorenzo A. Rewiring Endothelial Sphingolipid Metabolism to Favor S1P Over Ceramide Protects From Coronary Atherosclerosis. Circ Res. 2024;.

Yang L, Kim TWan, Han Y, Nair MS, Harschnitz O, Zhu J, Wang P, Koo SYeon, Lacko LA, Chandar V, Bram Y, Zhang T, Zhang W, He F, Pan C, Wu J, Huang Y, Evans T, van der Valk P, Titulaer MJ, Spoor JKH, O'Brien RLFurler, Bugiani M, Van de Berg WDJ, Schwartz RE, Ho DD, Studer L, Chen S. SARS-CoV-2 infection causes dopaminergic neuron senescence. Cell Stem Cell. 2024;.

Lin S, Schwartz TH, Pitt GS. Sudden Unexpected Death in Epilepsy: Respiratory vs. Cardiac Contributions. Cardiovasc Res. 2024;.

Bolzenius J, Sacdalan C, Ndhlovu LC, Sailasuta N, Trautmann L, Tipsuk S, Crowell TA, Suttichom D, Colby DJ, Phanuphak N, Chan P, Premeaux T, Kroon E, Vasan S, Hsu DC, Valcour V, Ananworanich J, Robb ML, Ake JA, Pohl KM, Sriplienchan S, Spudich S, Paul R. Brain volumetrics differ by Fiebig stage in acute HIV infection. AIDS. 2023;37(6):861-869.