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Found 42 results
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2024
Katchman AN
,
Zakharov SI
,
Bohnen MS
,
Jimenez ASanchez
,
Kushner JS
,
Yang L
,
Chen B-X
,
Nasari A
,
Liu G
,
Rabbani DE
,
Han J
,
Leu C-S
,
Pitt GS
,
Marx SO
.
Augmented Cardiac Inotropy by Phosphodiesterase Inhibition Requires Phosphorylation of Rad and Increased Calcium Current.
Circulation. 2024;149(20):1617-1620.
Papa A
,
Morfin PJDel Rive
,
Chen B-X
,
Yang L
,
Katchman AN
,
Zakharov SI
,
Liu G
,
Bohnen MS
,
Zheng V
,
Katz M
,
Subramaniam S
,
Hirsch JA
,
Weiss S
,
Dascal N
,
Karlin A
,
Pitt GS
,
Colecraft HM
,
Ben Johny M
,
Marx SO
.
A membrane-associated phosphoswitch in Rad controls adrenergic regulation of cardiac calcium channels.
J Clin Invest. 2024;.
Yang L
,
Kim TWan
,
Han Y
,
Nair MS
,
Harschnitz O
,
Zhu J
,
Wang P
,
Koo SYeon
,
Lacko LA
,
Chandar V
,
Bram Y
,
Zhang T
,
Zhang W
,
He F
,
Pan C
,
Wu J
,
Huang Y
,
Evans T
,
van der Valk P
,
Titulaer MJ
,
Spoor JKH
,
O'Brien RLFurler
,
Bugiani M
,
Van de Berg WDJ
,
Schwartz RE
,
Ho DD
,
Studer L
,
Chen S
.
SARS-CoV-2 infection causes dopaminergic neuron senescence.
Cell Stem Cell. 2024;.
2023
Das BC
,
Yadav P
,
Das S
,
Saito M
,
Evans T
.
Development of a New Methodology for Dearomative Borylation of Coumarins and Chromenes and Its Applications to Synthesize Boron-Containing Retinoids.
Molecules. 2023;28(3).
Premeaux TA
,
Yeung ST
,
Pillai SK
,
Ndhlovu LC
.
Elevated Galectin-9 across the human brain correlates with HIV neuropathology and detrimental cognitive states.
J Neurovirol. 2023;.
Yang L
,
Arbona RJRicart
,
Smith CS
,
Banks KM
,
V Thomas K
,
Palmer L
,
Evans T
,
Hurtado R
.
An evolutionarily conserved pacemaker role for HCN ion channels in smooth muscle.
J Physiol. 2023;601(7):1225-1246.
Du L
,
Bouzidi MS
,
Gala A
,
Deiter F
,
Billaud J-N
,
Yeung ST
,
Dabral P
,
Jin J
,
Simmons G
,
Dossani ZY
,
Niki T
,
Ndhlovu LC
,
Greenland JR
,
Pillai SK
.
Human galectin-9 potently enhances SARS-CoV-2 replication and inflammation in airway epithelial cells.
J Mol Cell Biol. 2023;15(4).
Yang L
,
Han Y
,
Zhou T
,
Lacko LA
,
Saeed M
,
Tan C
,
Danziger R
,
Zhu J
,
Zhao Z
,
Cahir C
,
Giani AMaria
,
Li Y
,
Dong X
,
Moroziewicz D
,
Paull D
,
Chen Z
,
Zhong A
,
Noggle SA
,
Rice CM
,
Qi Q
,
Evans T
,
Chen S
.
Isogenic human trophectoderm cells demonstrate the role of NDUFA4 and associated variants in ZIKV infection.
iScience. 2023;26(7):107001.
Bakis I
,
Sun Y
,
Elmagid LAbd
,
Feng X
,
Garibyan M
,
Yip J
,
Yu FZhou
,
Chowdhary S
,
Fernandez E
,
Cao J
,
McCain M
,
Lien C-L
,
Harrison MRm
.
Methods for dynamic and whole volume imaging of the zebrafish heart.
Dev Biol. 2023;.
Bakis I
,
Sun Y
,
Elmagid LAbd
,
Feng X
,
Garibyan M
,
Yip J
,
Yu FZhou
,
Chowdhary S
,
Fernandez E
,
Cao J
,
McCain M
,
Lien C-L
,
Harrison MRm
.
Methods for dynamic and whole volume imaging of the zebrafish heart.
Dev Biol. 2023;.
Yammine L
,
Picatoste B
,
Abdullah N
,
Leahey RA
,
Johnson EF
,
Gómez-Banoy N
,
Rosselot C
,
Wen J
,
Hossain T
,
Goncalves MD
,
Lo JC
,
Garcia-Ocana A
,
McGraw TE
.
Spatiotemporal regulation of GIPR signaling impacts glucose homeostasis as revealed in studies of a common GIPR variant.
Mol Metab. 2023;:101831.
2022
Xia Y
,
Duca S
,
Perder B
,
Dündar F
,
Zumbo P
,
Qiu M
,
Yao J
,
Cao Y
,
Harrison MRM
,
Zangi L
,
Betel D
,
Cao J
.
Activation of a transient progenitor state in the epicardium is required for zebrafish heart regeneration.
Nat Commun. 2022;13(1):7704.
Yeung ST
,
Premeaux TA
,
Du L
,
Niki T
,
Pillai SK
,
Khanna KM
,
Ndhlovu LC
.
Galectin-9 protects humanized-ACE2 immunocompetent mice from SARS-CoV-2 infection.
Front Immunol. 2022;13:1011185.
Farhadian SF
,
Lindenbaum O
,
Zhao J
,
Corley MJ
,
Im Y
,
Walsh H
,
Vecchio A
,
Garcia-Milian R
,
Chiarella J
,
Chintanaphol M
,
Calvi R
,
Wang G
,
Ndhlovu LC
,
Yoon J
,
Trotta D
,
Ma S
,
Kluger Y
,
Spudich S
.
HIV viral transcription and immune perturbations in the CNS of people with HIV despite ART.
JCI Insight. 2022;7(13).
Han Y
,
Tan L
,
Zhou T
,
Yang L
,
Carrau L
,
Lacko LA
,
Saeed M
,
Zhu J
,
Zhao Z
,
Nilsson-Payant BE
,
Neto FTenorio Li
,
Cahir C
,
Giani AMaria
,
Chai JChou
,
Li Y
,
Dong X
,
Moroziewicz D
,
Paull D
,
Zhang T
,
Koo S
,
Tan C
,
Danziger R
,
Ba Q
,
Feng L
,
Chen Z
,
Zhong A
,
Wise GJ
,
Xiang JZ
,
Wang H
,
Schwartz RE
,
tenOever BR
,
Noggle SA
,
Rice CM
,
Qi Q
,
Evans T
,
Chen S
.
A human iPSC-array-based GWAS identifies a virus susceptibility locus in the NDUFA4 gene and functional variants.
Cell Stem Cell. 2022;29(10):1475-1490.e6.
Lee D
,
Le Pen J
,
Yatim A
,
Dong B
,
Aquino Y
,
Ogishi M
,
Pescarmona R
,
Talouarn E
,
Rinchai D
,
Zhang P
,
Perret M
,
Liu Z
,
Jordan I
,
Bozdemir SElmas
,
Bayhan GIclal
,
Beaufils C
,
Bizien L
,
Bisiaux A
,
Lei W
,
Hasan M
,
Chen J
,
Gaughan C
,
Asthana A
,
Libri V
,
Luna JM
,
Jaffré F
,
Hoffmann H-H
,
Michailidis E
,
Moreews M
,
Seeleuthner Y
,
Bilguvar K
,
Mane S
,
Flores C
,
Zhang Y
,
Arias AA
,
Bailey R
,
Schlüter A
,
Milisavljevic B
,
Bigio B
,
Le Voyer T
,
Materna M
,
Gervais A
,
Moncada-Velez M
,
Pala F
,
Lazarov T
,
Levy R
,
Neehus A-L
,
Rosain J
,
Peel J
,
Chan Y-H
,
Morin M-P
,
Pino-Ramirez RMaria
,
Belkaya S
,
Lorenzo L
,
Anton J
,
Delafontaine S
,
Toubiana J
,
Bajolle F
,
Fumadó V
,
DeDiego ML
,
Fidouh N
,
Rozenberg F
,
Pérez-Tur J
,
Chen S
,
Evans T
,
Geissmann F
,
Lebon P
,
Weiss SR
,
Bonnet D
,
Duval X
,
Covid HGenetic Ef
,
Pan-Hammarström Q
,
Planas AM
,
Meyts I
,
Haerynck F
,
Pujol A
,
Sancho-Shimizu V
,
Dalgard C
,
Bustamante J
,
Puel A
,
Boisson-Dupuis S
,
Boisson B
,
Maniatis T
,
Zhang Q
,
Bastard P
,
Notarangelo L
,
Béziat V
,
de Diego RPerez
,
Rodriguez-Gallego C
,
Su HC
,
Lifton RP
,
Jouanguy E
,
Cobat A
,
Alsina L
,
Keles S
,
Haddad E
,
Abel L
,
Belot A
,
Quintana-Murci L
,
Rice CM
, et al.
.
Inborn errors of OAS-RNase L in SARS-CoV-2-related multisystem inflammatory syndrome in children.
Science. 2022;:eabo3627.
Papa A
,
Zakharov SI
,
Katchman AN
,
Kushner JS
,
Chen B-X
,
Yang L
,
Liu G
,
Jimenez ASanchez
,
Eisert RJ
,
Bradshaw GA
,
Dun W
,
Ali SR
,
Rodriques A
,
Zhou K
,
Topkara V
,
Yang M
,
Morrow JP
,
Tsai EJ
,
Karlin A
,
Wan E
,
Kalocsay M
,
Pitt GS
,
Colecraft HM
,
Ben-Johny M
,
Marx SO
.
Rad regulation of CaV1.2 channels controls cardiac fight-or-flight response.
Nat Cardiovasc Res. 2022;1(11):1022-1038.
Papa A
,
Zakharov SI
,
Katchman AN
,
Kushner JS
,
Chen B-X
,
Yang L
,
Liu G
,
Jimenez ASanchez
,
Eisert RJ
,
Bradshaw GA
,
Dun W
,
Ali SR
,
Rodriques A
,
Zhou K
,
Topkara V
,
Yang M
,
Morrow JP
,
Tsai EJ
,
Karlin A
,
Wan E
,
Kalocsay M
,
Pitt GS
,
Colecraft HM
,
Ben-Johny M
,
Marx SO
.
Rad regulation of CaV1.2 channels controls cardiac fight-or-flight response.
Nat Cardiovasc Res. 2022;1(11):1022-1038.
Han Y
,
Zhu J
,
Yang L
,
Nilsson-Payant BE
,
Hurtado R
,
Lacko LA
,
Sun X
,
Gade AR
,
Higgins CA
,
Sisso WJ
,
Dong X
,
Wang M
,
Chen Z
,
Ho DD
,
Pitt GS
,
Schwartz RE
,
tenOever BR
,
Evans T
,
Chen S
.
SARS-CoV-2 Infection Induces Ferroptosis of Sinoatrial Node Pacemaker Cells.
Circ Res. 2022;130(7):963-977.
2021
Yang L
,
Nilsson-Payant BE
,
Han Y
,
Jaffré F
,
Zhu J
,
Wang P
,
Zhang T
,
Redmond D
,
Houghton S
,
Møller R
,
Hoagland D
,
Carrau L
,
Horiuchi S
,
Goff M
,
Lim JK
,
Bram Y
,
Richardson C
,
Chandar V
,
Borczuk A
,
Huang Y
,
Xiang J
,
Ho DD
,
Schwartz RE
,
tenOever BR
,
Evans T
,
Chen S
.
Cardiomyocytes recruit monocytes upon SARS-CoV-2 infection by secreting CCL2.
Stem Cell Reports. 2021;.
Yang L
,
Han Y
,
Jaffré F
,
Nilsson-Payant BE
,
Bram Y
,
Wang P
,
Zhu J
,
Zhang T
,
Redmond D
,
Houghton S
,
Uhl S
,
Borczuk A
,
Huang Y
,
Richardson C
,
Chandar V
,
Acklin JA
,
Lim JK
,
Xiang J
,
Ho DD
,
tenOever BR
,
Schwartz RE
,
Evans T
,
Chen Z
,
Chen S
.
An Immuno-Cardiac Model for Macrophage-Mediated Inflammation in COVID-19 Hearts.
Circ Res. 2021;.
Dixon G
,
Pan H
,
Yang D
,
Rosen BP
,
Jashari T
,
Verma N
,
Pulecio J
,
Caspi I
,
Lee K
,
Stransky S
,
Glezer A
,
Liu C
,
Rivas M
,
Kumar R
,
Lan Y
,
Torregroza I
,
He C
,
Sidoli S
,
Evans T
,
Elemento O
,
Huangfu D
.
QSER1 protects DNA methylation valleys from de novo methylation.
Science. 2021;372(6538).
2020
Yang L
,
Han Y
,
Nilsson-Payant BE
,
Gupta V
,
Wang P
,
Duan X
,
Tang X
,
Zhu J
,
Zhao Z
,
Jaffré F
,
Zhang T
,
Kim TWan
,
Harschnitz O
,
Redmond D
,
Houghton S
,
Liu C
,
Naji A
,
Ciceri G
,
Guttikonda S
,
Bram Y
,
Nguyen D-HT
,
Cioffi M
,
Chandar V
,
Hoagland DA
,
Huang Y
,
Xiang J
,
Wang H
,
Lyden D
,
Borczuk A
,
Chen HJoyce
,
Studer L
,
Pan FCheng
,
Ho DD
,
tenOever BR
,
Evans T
,
Schwartz RE
,
Chen S
.
A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids.
Cell Stem Cell. 2020;.
Han Y
,
Duan X
,
Yang L
,
Nilsson-Payant BE
,
Wang P
,
Duan F
,
Tang X
,
Yaron TM
,
Zhang T
,
Uhl S
,
Bram Y
,
Richardson C
,
Zhu J
,
Zhao Z
,
Redmond D
,
Houghton S
,
Nguyen D-HT
,
Xu D
,
Wang X
,
Jessurun J
,
Borczuk A
,
Huang Y
,
Johnson JL
,
Liu Y
,
Xiang J
,
Wang H
,
Cantley LC
,
tenOever BR
,
Ho DD
,
Pan FCheng
,
Evans T
,
Chen HJoyce
,
Schwartz RE
,
Chen S
.
Identification of SARS-CoV-2 Inhibitors using Lung and Colonic Organoids.
Nature. 2020;.
Han Y
,
Duan X
,
Yang L
,
Nilsson-Payant BE
,
Wang P
,
Duan F
,
Tang X
,
Yaron TM
,
Zhang T
,
Uhl S
,
Bram Y
,
Richardson C
,
Zhu J
,
Zhao Z
,
Redmond D
,
Houghton S
,
Nguyen D-HT
,
Xu D
,
Wang X
,
Jessurun J
,
Borczuk A
,
Huang Y
,
Johnson JL
,
Liu Y
,
Xiang J
,
Wang H
,
Cantley LC
,
tenOever BR
,
Ho DD
,
Pan FCheng
,
Evans T
,
Chen HJoyce
,
Schwartz RE
,
Chen S
.
Identification of SARS-CoV-2 Inhibitors using Lung and Colonic Organoids.
Nature. 2020;.
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