Publications

Crespo M, Vilar E, Tsai S-Y, Chang K, Amin S, Srinivasan T, Zhang T, Pipalia NH, Chen HJoyce, Witherspoon M et al..  2017.  Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing.. Nat Med. 23(7):878-884.

Swendeman SL, Xiong Y, Cantalupo A, Yuan H, Burg N, Hisano Y, Cartier A, Liu CH, Engelbrecht E, Blaho V et al..  2017.  An engineered S1P chaperone attenuates hypertension and ischemic injury.. Sci Signal. 10(492)

Ghazizadeh Z, Kao D-I, Amin S, Cook B, Rao S, Zhou T, Zhang T, Xiang Z, Kenyon R, Kaymakcalan O et al..  2017.  ROCKII inhibition promotes the maturation of human pancreatic beta-like cells.. Nat Commun. 8(1):298.

Guo M, Zhang T, Dong X, Xiang JZhaoying, Lei M, Evans T, Graumann J, Chen S.  2017.  Using hESCs to Probe the Interaction of the Diabetes-Associated Genes CDKAL1 and MT1E.. Cell Rep. 19(8):1512-1521.

Amin S, Cook B, Zhou T, Ghazizadeh Z, Lis R, Zhang T, Khalaj M, Crespo M, Perera M, Xiang JZhaoying et al..  2018.  Discovery of a drug candidate for GLIS3-associated diabetes.. Nat Commun. 9(1):2681.

Zhou T, Kim TWan, Chong CNok, Tan L, Amin S, Badieyan ZSadat, Mukherjee S, Ghazizadeh Z, Zeng H, Guo M et al..  2018.  A hPSC-based platform to discover gene-environment interactions that impact human β-cell and dopamine neuron survival.. Nat Commun. 9(1):4815.

Xu R, Yallowitz A, Qin A, Wu Z, Shin DYeon, Kim J-M, Debnath S, Ji G, Bostrom MP, Yang X et al..  2018.  Targeting skeletal endothelium to ameliorate bone loss.. Nat Med. 24(6):823-833.

Li QV, Dixon G, Verma N, Rosen BP, Gordillo M, Luo R, Xu C, Wang Q, Soh C-L, Yang D et al..  2019.  Genome-scale screens identify JNK-JUN signaling as a barrier for pluripotency exit and endoderm differentiation.. Nat Genet. 51(6):999-1010.

Li QV, Dixon G, Verma N, Rosen BP, Gordillo M, Luo R, Xu C, Wang Q, Soh C-L, Yang D et al..  2019.  Genome-scale screens identify JNK-JUN signaling as a barrier for pluripotency exit and endoderm differentiation.. Nat Genet. 51(6):999-1010.

Barry DM, McMillan EA, Kunar B, Lis R, Zhang T, Lu T, Daniel E, Yokoyama M, Gomez-Salinero JM, Sureshbabu A et al..  2019.  Molecular determinants of nephron vascular specialization in the kidney.. Nat Commun. 10(1):5705.

Yang L, Han Y, Nilsson-Payant BE, Gupta V, Wang P, Duan X, Tang X, Zhu J, Zhao Z, Jaffré F et al..  2020.  A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids.. Cell Stem Cell.

Han Y, Duan X, Yang L, Nilsson-Payant BE, Wang P, Duan F, Tang X, Yaron TM, Zhang T, Uhl S et al..  2020.  Identification of SARS-CoV-2 Inhibitors using Lung and Colonic Organoids.. Nature.

Han Y, Duan X, Yang L, Nilsson-Payant BE, Wang P, Duan F, Tang X, Yaron TM, Zhang T, Uhl S et al..  2020.  Identification of SARS-CoV-2 Inhibitors using Lung and Colonic Organoids.. Nature.

Yang L, Nilsson-Payant BE, Han Y, Jaffré F, Zhu J, Wang P, Zhang T, Redmond D, Houghton S, Møller R et al..  2021.  Cardiomyocytes recruit monocytes upon SARS-CoV-2 infection by secreting CCL2.. Stem Cell Reports.

Yang L, Han Y, Jaffré F, Nilsson-Payant BE, Bram Y, Wang P, Zhu J, Zhang T, Redmond D, Houghton S et al..  2021.  An Immuno-Cardiac Model for Macrophage-Mediated Inflammation in COVID-19 Hearts.. Circ Res.

Xia Y, Duca S, Perder B, Dündar F, Zumbo P, Qiu M, Yao J, Cao Y, Harrison MRM, Zangi L et al..  2022.  Activation of a transient progenitor state in the epicardium is required for zebrafish heart regeneration.. Nat Commun. 13(1):7704.

Ghazizadeh Z, Zhu J, Fattahi F, Tang A, Sun X, Amin S, Tsai S-Y, Khalaj M, Zhou T, Samuel RM et al..  2022.  A dual SHOX2:GFP; MYH6:mCherry knockin hESC reporter line for derivation of human SAN-like cells.. iScience. 25(4):104153.

Han Y, Tan L, Zhou T, Yang L, Carrau L, Lacko LA, Saeed M, Zhu J, Zhao Z, Nilsson-Payant BE et al..  2022.  A human iPSC-array-based GWAS identifies a virus susceptibility locus in the NDUFA4 gene and functional variants.. Cell Stem Cell. 29(10):1475-1490.e6.

Cao Y, Xia Y, Balowski JJ, Ou J, Song L, Safi A, Curtis T, Crawford GE, Poss KD, Cao J.  2022.  Identification of enhancer regulatory elements that direct epicardial gene expression during zebrafish heart regeneration.. Development. 149(4)

Cortada E, Yao J, Xia Y, Dündar F, Zumbo P, Yang B, Rubio-Navarro A, Perder B, Qiu M, Pettinato AM et al..  2024.  Cross-species single-cell RNA-seq analysis reveals disparate and conserved cardiac and extracardiac inflammatory responses upon heart injury.. Commun Biol. 7(1):1611.

Duca S, Xia Y, Elmagid LAbd, Bakis I, Qiu M, Cao Y, Guo Y, Eichenbaum JV, McCain ML, Kang J et al..  2024.  Differential vegfc expression dictates lymphatic response during zebrafish heart development and regeneration.. Development. 151(22)

Yang L, Han Y, Zhang T, Dong X, Ge J, Roy A, Zhu J, Lu T, J Vandana J, de Silva N et al..  2024.  Human vascularized macrophage-islet organoids to model immune-mediated pancreatic β cell pyroptosis upon viral infection.. Cell Stem Cell.

Lyu S, Yao AGea Chen, Xia Y, Cao J.  2025.  Advances in Epicardial Biology: Insights from Development, Regeneration, and Human Cardiac Organoids.. J Cardiovasc Dev Dis. 12(10)

Zhu J, Li Z, Xue D, Meng Z, Shao S, Pulecio J, Zhang G, Huangfu D, Evans T, Schultz PG et al..  2025.  A Chemical Epigenetic Probe to Capture the Site-Specific DNA-Binding Protein Complex.. Res Sq.

Zhu J, Li Z, Xue D, Meng Z, Shao S, Pulecio J, Zhang G, Huangfu D, Evans T, Chen S et al..  2025.  A chemical epigenetic tool to probe site-specific DNA-binding protein complexes.. Proc Natl Acad Sci U S A. 122(40):e2509021122.