Publications

Farber G, Parks MM, Guahmich NLustgarten, Zhang Y, Monette S, Blanchard SC, Di Lorenzo A, Blobel CP. ADAM10 controls the differentiation of the coronary arterial endothelium. Angiogenesis. 2018;.

Amin S, Cook B, Zhou T, Ghazizadeh Z, Lis R, Zhang T, Khalaj M, Crespo M, Perera M, Xiang JZhaoying, Zhu Z, Tomishima M, Liu C, Naji A, Evans T, Huangfu D, Chen S. Discovery of a drug candidate for GLIS3-associated diabetes. Nat Commun. 2018;9(1):2681.

Zhou T, Kim TWan, Chong CNok, Tan L, Amin S, Badieyan ZSadat, Mukherjee S, Ghazizadeh Z, Zeng H, Guo M, Crespo M, Zhang T, Kenyon R, Robinson CL, Apostolou E, Wang H, Xiang JZhaoying, Evans T, Studer L, Chen S. A hPSC-based platform to discover gene-environment interactions that impact human β-cell and dopamine neuron survival. Nat Commun. 2018;9(1):4815.

Zhou T, Kim TWan, Chong CNok, Tan L, Amin S, Badieyan ZSadat, Mukherjee S, Ghazizadeh Z, Zeng H, Guo M, Crespo M, Zhang T, Kenyon R, Robinson CL, Apostolou E, Wang H, Xiang JZhaoying, Evans T, Studer L, Chen S. A hPSC-based platform to discover gene-environment interactions that impact human β-cell and dopamine neuron survival. Nat Commun. 2018;9(1):4815.

Ghazizadeh Z, Fattahi F, Mirzaei M, Bayersaikhan D, Lee J, Chae S, Hwang D, Byun K, Tabar MSharifi, Taleahmad S, Mirshahvaladi S, Shabani P, Fonoudi H, Haynes PA, Baharvand H, Aghdami N, Evans T, Lee B, Salekdeh GHosseini. Prospective Isolation of ISL1 Cardiac Progenitors from Human ESCs for Myocardial Infarction Therapy. Stem Cell Reports. 2018;10(3):848-859.

Xu R, Yallowitz A, Qin A, Wu Z, Shin DYeon, Kim J-M, Debnath S, Ji G, Bostrom MP, Yang X, Zhang C, Dong H, Kermani P, Lalani S, Li N, Liu Y, Poulos MG, Wach A, Zhang Y, Inoue K, Di Lorenzo A, Zhao B, Butler JM, Shim J-H, Glimcher LH, Greenblatt MB. Targeting skeletal endothelium to ameliorate bone loss. Nat Med. 2018;24(6):823-833.

Xu R, Yallowitz A, Qin A, Wu Z, Shin DYeon, Kim J-M, Debnath S, Ji G, Bostrom MP, Yang X, Zhang C, Dong H, Kermani P, Lalani S, Li N, Liu Y, Poulos MG, Wach A, Zhang Y, Inoue K, Di Lorenzo A, Zhao B, Butler JM, Shim J-H, Glimcher LH, Greenblatt MB. Targeting skeletal endothelium to ameliorate bone loss. Nat Med. 2018;24(6):823-833.

Ortega FA, Grandi E, Krogh-Madsen T, Christini DJ. Applications of Dynamic Clamp to Cardiac Arrhythmia Research: Role in Drug Target Discovery and Safety Pharmacology Testing. Front Physiol. 2017;8:1099.

Crespo M, Vilar E, Tsai S-Y, Chang K, Amin S, Srinivasan T, Zhang T, Pipalia NH, Chen HJoyce, Witherspoon M, Gordillo M, Xiang JZhaoying, Maxfield FR, Lipkin S, Evans T, Chen S. Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing. Nat Med. 2017;23(7):878-884.

Devenyi RA, Ortega FA, Groenendaal W, Krogh-Madsen T, Christini DJ, Sobie EA. Differential roles of two delayed rectifier potassium currents in regulation of ventricular action potential duration and arrhythmia susceptibility. J Physiol. 2017;595(7):2301-2317.

Swendeman SL, Xiong Y, Cantalupo A, Yuan H, Burg N, Hisano Y, Cartier A, Liu CH, Engelbrecht E, Blaho V, Zhang Y, Yanagida K, Galvani S, Obinata H, Salmon JE, Sanchez T, Di Lorenzo A, Hla T. An engineered S1P chaperone attenuates hypertension and ischemic injury. Sci Signal. 2017;10(492).

Gómez-Banoy N, Lo JC. Genetic Manipulation with Viral Vectors to Assess Metabolism and Adipose Tissue Function. Methods Mol Biol. 2017;1566:109-124.

Patel YA, George A, Dorval AD, White JA, Christini DJ, Butera RJ. Hard real-time closed-loop electrophysiology with the Real-Time eXperiment Interface (RTXI). PLoS Comput Biol. 2017;13(5):e1005430.

Cao C, Ren Y, Barnett AS, Mirando AJ, Rouse D, Mun SHwan, Park-Min K-H, McNulty AL, Guilak F, Karner CM, Hilton MJ, Pitt GS. Increased Ca2+ signaling through CaV1.2 promotes bone formation and prevents estrogen deficiency-induced bone loss. JCI Insight. 2017;2(22).

Ghazizadeh Z, Kao D-I, Amin S, Cook B, Rao S, Zhou T, Zhang T, Xiang Z, Kenyon R, Kaymakcalan O, Liu C, Evans T, Chen S. ROCKII inhibition promotes the maturation of human pancreatic beta-like cells. Nat Commun. 2017;8(1):298.

Cantalupo A, Gargiulo A, Dautaj E, Liu C, Zhang Y, Hla T, Di Lorenzo A. S1PR1 (Sphingosine-1-Phosphate Receptor 1) Signaling Regulates Blood Flow and Pressure. Hypertension. 2017;70(2):426-434.

Guo M, Zhang T, Dong X, Xiang JZhaoying, Lei M, Evans T, Graumann J, Chen S. Using hESCs to Probe the Interaction of the Diabetes-Associated Genes CDKAL1 and MT1E. Cell Rep. 2017;19(8):1512-1521.

Guo M, Zhang T, Dong X, Xiang JZhaoying, Lei M, Evans T, Graumann J, Chen S. Using hESCs to Probe the Interaction of the Diabetes-Associated Genes CDKAL1 and MT1E. Cell Rep. 2017;19(8):1512-1521.

Zhang Y, Huang Y, Cantalupo A, Azevedo PS, Siragusa M, Bielawski J, Giordano FJ, Di Lorenzo A. Endothelial Nogo-B regulates sphingolipid biosynthesis to promote pathological cardiac hypertrophy during chronic pressure overload. JCI Insight. 2016;1(5).

Wang H-G, Zhu W, Kanter RJ, Silva JR, Honeywell C, Gow RM, Pitt GS. A novel NaV1.5 voltage sensor mutation associated with severe atrial and ventricular arrhythmias. J Mol Cell Cardiol. 2016;92:52-62.

Svensson KJ, Long JZ, Jedrychowski MP, Cohen P, Lo JC, Serag S, Kir S, Shinoda K, Tartaglia JA, Rao RR, Chédotal A, Kajimura S, Gygi SP, Spiegelman BM. A Secreted Slit2 Fragment Regulates Adipose Tissue Thermogenesis and Metabolic Function. Cell Metab. 2016;23(3):454-66.

Cao J, Navis A, Cox BD, Dickson AL, Gemberling M, Karra R, Bagnat M, Poss KD. Single epicardial cell transcriptome sequencing identifies Caveolin 1 as an essential factor in zebrafish heart regeneration. Development. 2016;143(2):232-43.

Liu D, Lei L, Desir M, Huang Y, Cleman J, Jiang W, Fernandez-Hernando C, Di Lorenzo A, Sessa WC, Giordano FJ. Smooth Muscle Hypoxia-Inducible Factor 1α Links Intravascular Pressure and Atherosclerosis--Brief Report. Arterioscler Thromb Vasc Biol. 2016;36(3):442-5.

Black JB, Adler AF, Wang H-G, D'Ippolito AM, Hutchinson HA, Reddy TE, Pitt GS, Leong KW, Gersbach CA. Targeted Epigenetic Remodeling of Endogenous Loci by CRISPR/Cas9-Based Transcriptional Activators Directly Converts Fibroblasts to Neuronal Cells. Cell Stem Cell. 2016;19(3):406-14.