Publications

Liu Y, Choi T, Pearson B, Nachman R, Woo W, Xu N, Schreiner R, Hurtado R, Seandel M, Rafii S et al..  2026.  Restoration of Spermatogenesis is Dependent on Activation of a SPRY4-ERK Checkpoint Following Germline Stem Cell Damage.. Biol Reprod.

Manzo OLaura, Nour J, Sasset L, Marino A, Rubinelli L, Palikhe S, Smimmo M, Hu Y, Bucci MRosaria, Borczuk A et al..  2024.  Rewiring Endothelial Sphingolipid Metabolism to Favor S1P Over Ceramide Protects From Coronary Atherosclerosis.. Circ Res.

Ghazizadeh Z, Kao D-I, Amin S, Cook B, Rao S, Zhou T, Zhang T, Xiang Z, Kenyon R, Kaymakcalan O et al..  2017.  ROCKII inhibition promotes the maturation of human pancreatic beta-like cells.. Nat Commun. 8(1):298.

Sasset L, Chowdhury KH, Manzo OL, Rubinelli L, Konrad C, Maschek JA, Manfredi G, Holland WL, Di Lorenzo A.  2022.  S1P controls endothelial sphingolipid homeostasis via ORMDL.. FASEB J. 36 Suppl 1

Cantalupo A, Di Lorenzo A.  2016.  S1P Signaling and De Novo Biosynthesis in Blood Pressure Homeostasis.. J Pharmacol Exp Ther. 358(2):359-70.

Cantalupo A, Gargiulo A, Dautaj E, Liu C, Zhang Y, Hla T, Di Lorenzo A.  2017.  S1PR1 (Sphingosine-1-Phosphate Receptor 1) Signaling Regulates Blood Flow and Pressure.. Hypertension. 70(2):426-434.

Yang L, Kim TWan, Han Y, Nair MS, Harschnitz O, Zhu J, Wang P, Koo SYeon, Lacko LA, Chandar V et al..  2024.  SARS-CoV-2 infection causes dopaminergic neuron senescence.. Cell Stem Cell.

Han Y, Zhu J, Yang L, Nilsson-Payant BE, Hurtado R, Lacko LA, Sun X, Gade AR, Higgins CA, Sisso WJ et al..  2022.  SARS-CoV-2 Infection Induces Ferroptosis of Sinoatrial Node Pacemaker Cells.. Circ Res. 130(7):963-977.

Wang H-G, Bavley CC, Li A, Jones RM, Hackett J, Bayleyen Y, Lee FS, Rajadhyaksha AM, Pitt GS.  2021.  Scn2a severe hypomorphic mutation decreases excitatory synaptic input and causes autism-associated behaviors.. JCI Insight. 6(15)

Svensson KJ, Long JZ, Jedrychowski MP, Cohen P, Lo JC, Serag S, Kir S, Shinoda K, Tartaglia JA, Rao RR et al..  2016.  A Secreted Slit2 Fragment Regulates Adipose Tissue Thermogenesis and Metabolic Function.. Cell Metab. 23(3):454-66.

Gilani A, Stein BD, Hoffmann A, de Lima RPereira, Ha EE, Homan EA, Ma L, Rubio-Navarro A, Wun TTha Ra, Carrascal GJose Ayala et al..  2025.  Secretory kinase FAM20C triggers adipocyte dysfunction inciting insulin resistance and inflammation in obesity.. J Clin Invest.

Cao J, Navis A, Cox BD, Dickson AL, Gemberling M, Karra R, Bagnat M, Poss KD.  2016.  Single epicardial cell transcriptome sequencing identifies Caveolin 1 as an essential factor in zebrafish heart regeneration.. Development. 143(2):232-43.

Krogh-Madsen T, Christini DJ.  2017.  Slow [Na+]i dynamics impacts arrhythmogenesis and spiral wave reentry in cardiac myocyte ionic model.. Chaos. 27(9):093907.

Cook B, Walker N, Zhang Q, Chen S, Evans T.  2021.  The small molecule DIPQUO promotes osteogenic differentiation via inhibition of glycogen synthase kinase 3 β signaling.. J Biol Chem. :100696.

Liu D, Lei L, Desir M, Huang Y, Cleman J, Jiang W, Fernandez-Hernando C, Di Lorenzo A, Sessa WC, Giordano FJ.  2016.  Smooth Muscle Hypoxia-Inducible Factor 1α Links Intravascular Pressure and Atherosclerosis--Brief Report.. Arterioscler Thromb Vasc Biol. 36(3):442-5.

Nana BChristine, Esemu LForgu, Besong MEbangha, Atchombat DHyacinthe, Ogai K, Sobgui TMPatricia, Nana CMarco Mbia, Seumko'o RMedouen Nd, Awanakan H, Ekali GLoni et al..  2023.  Soluble biomarkers of HIV-1-related systemic immune activation are associated with high plasma levels of growth factors implicated in the pathogenesis of Kaposi sarcoma in adults.. Front Immunol. 14:1216480.

Joglekar A, Prjibelski A, Mahfouz A, Collier P, Lin S, Schlusche AKatharina, Marrocco J, Williams SR, Haase B, Hayes A et al..  2021.  A spatially resolved brain region- and cell type-specific isoform atlas of the postnatal mouse brain. Nat Commun. 12(1):463.

Yammine L, Picatoste B, Abdullah N, Leahey RA, Johnson EF, Gómez-Banoy N, Rosselot C, Wen J, Hossain T, Goncalves MD et al..  2023.  Spatiotemporal regulation of GIPR signaling impacts glucose homeostasis as revealed in studies of a common GIPR variant.. Mol Metab. :101831.

Sam J, Mercer EJ, Torregroza I, Banks KM, Evans T.  2020.  Specificity, redundancy and dosage thresholds among genes during zebrafish cardiogenesis.. Biol Open. 9(6)

Sasset L, Zhang Y, Dunn TM, Di Lorenzo A.  2016.  Sphingolipid De Novo Biosynthesis: A Rheostat of Cardiovascular Homeostasis.. Trends Endocrinol Metab. 27(11):807-819.

Pandey S, Banks KM, Kumar R, Kuo A, Wen D, Hla T, Evans T.  2020.  Sphingosine Kinases Protect Murine ESCs from Sphingosine-induced Cell Cycle Arrest.. Stem Cells.

Sasset L, Chowdhury KH, Manzo OL, Rubinelli L, Konrad C, J Maschek A, Manfredi G, Holland WL, Di Lorenzo A.  2022.  Sphingosine-1-phosphate controls endothelial sphingolipid homeostasis via ORMDL.. EMBO Rep. :e54689.

Di Lorenzo A.  2020.  Sphingosine-1-phosphate receptor-1 (S1PR1) signaling: the homeostatic pathway of the heart.. Cardiovasc Res.

Zhang F, Evans T.  2025.  Stage-specific DNA methylation dynamics in mammalian heart development.. Epigenomics. :1-13.

Falzone ME, Rheinberger J, Lee B-C, Peyear T, Sasset L, Raczkowski AM, Eng ET, Di Lorenzo A, Andersen OS, Nimigean CM et al..  2019.  Structural basis of Ca-dependent activation and lipid transport by a TMEM16 scramblase.. Elife. 8