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Found 12 results
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Christini, David J
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Journal Article
Ortega FA
,
Grandi E
,
Krogh-Madsen T
,
Christini DJ
.
Applications of Dynamic Clamp to Cardiac Arrhythmia Research: Role in Drug Target Discovery and Safety Pharmacology Testing.
Front Physiol. 2017;8:1099.
Brown TR
,
Krogh-Madsen T
,
Christini DJ
.
Computational Approaches to Understanding the Role of Fibroblast-Myocyte Interactions in Cardiac Arrhythmogenesis.
Biomed Res Int. 2015;2015:465714.
Devenyi RA
,
Ortega FA
,
Groenendaal W
,
Krogh-Madsen T
,
Christini DJ
,
Sobie EA
.
Differential roles of two delayed rectifier potassium currents in regulation of ventricular action potential duration and arrhythmia susceptibility.
J Physiol. 2017;595(7):2301-2317.
Ghazizadeh Z
,
Zhu J
,
Fattahi F
,
Tang A
,
Sun X
,
Amin S
,
Tsai S-Y
,
Khalaj M
,
Zhou T
,
Samuel RM
,
Zhang T
,
Ortega FA
,
Gordillo M
,
Moroziewicz D
,
Paull D
,
Noggle SA
,
Xiang JZhaoying
,
Studer L
,
Christini DJ
,
Pitt GS
,
Evans T
,
Chen S
.
A dual SHOX2:GFP; MYH6:mCherry knockin hESC reporter line for derivation of human SAN-like cells.
iScience. 2022;25(4):104153.
Krogh-Madsen T
,
Jacobson AF
,
Ortega FA
,
Christini DJ
.
Global Optimization of Ventricular Myocyte Model to Multi-Variable Objective Improves Predictions of Drug-Induced Torsades de Pointes.
Front Physiol. 2017;8:1059.
Patel YA
,
George A
,
Dorval AD
,
White JA
,
Christini DJ
,
Butera RJ
.
Hard real-time closed-loop electrophysiology with the Real-Time eXperiment Interface (RTXI).
PLoS Comput Biol. 2017;13(5):e1005430.
Tsai S-Y
,
Ghazizadeh Z
,
Wang H-J
,
Ortega FA
,
Badieyan ZS
,
Hsu Z-T
,
Gordillo M
,
Kumar R
,
Christini DJ
,
Evans T
,
Chen S
.
A Human Embryonic Stem Cell Reporter Line for Monitoring Chemical-induced Cardiotoxicity.
Cardiovasc Res. 2019;.
Brown TR
,
Krogh-Madsen T
,
Christini DJ
.
Illuminating Myocyte-Fibroblast Homotypic and Heterotypic Gap Junction Dynamics Using Dynamic Clamp.
Biophys J. 2016;111(4):785-97.
Krogh-Madsen T
,
Sobie EA
,
Christini DJ
.
Improving cardiomyocyte model fidelity and utility via dynamic electrophysiology protocols and optimization algorithms.
J Physiol. 2016;594(9):2525-36.
Quach B
,
Krogh-Madsen T
,
Entcheva E
,
Christini DJ
.
Light-Activated Dynamic Clamp Using iPSC-Derived Cardiomyocytes.
Biophys J. 2018;115(11):2206-2217.
Krogh-Madsen T
,
Christini DJ
.
Slow [Na+]i dynamics impacts arrhythmogenesis and spiral wave reentry in cardiac myocyte ionic model.
Chaos. 2017;27(9):093907.
Gaur N
,
Ortega F
,
Verkerk AO
,
Mengarelli I
,
Krogh-Madsen T
,
Christini DJ
,
Coronel R
,
Vigmond EJ
.
Validation of quantitative measure of repolarization reserve as a novel marker of drug induced proarrhythmia.
J Mol Cell Cardiol. 2020;.