Publications

Azcona JA, Wacker AS, Lee C-H, Fung EK, Jeitner TM, Manzo OL, Di Lorenzo A, Babich JW, Amor-Coarasa A, Kelly JM. 2-[18F]Fluoropropionic Acid PET Imaging of Doxorubicin-Induced Cardiotoxicity. Mol Imaging Biol. 2025;27(1):109-119.

de Lima RPereira, Li A, Gilani A, Rubio-Navarro A, Warren CD, Kong IY, Geri JB, Lo JC. C3aR1 on β cells Enhances β cell Function and Survival to Maintain Glucose Homeostasis. Mol Metab. 2025;:102134.

Naderi J, Johnson AKelsey, Thakkar H, Chandravanshi B, Ksiazek A, Anand A, Vincent V, Tran A, Kalimireddy A, Singh P, Sood A, Das A, Talbot CLamar, Distefano IA, J Maschek A, Cox J, Li Y, Summers SA, Atkinson DJ, Turapov T, Ratcliff JA, Fung J, Shabbir A, M Yassin S, Shiow S-AToh Ee, Holland WL, Pitt GS, Chaurasia B. Ceramide-induced FGF13 impairs systemic metabolic health. Cell Metab. 2025;.

Zhu J, Li Z, Xue D, Meng Z, Shao S, Pulecio J, Zhang G, Huangfu D, Evans T, Schultz PG, Chen S. A Chemical Epigenetic Probe to Capture the Site-Specific DNA-Binding Protein Complex. Res Sq. 2025;.

J Vandana J, Zhu J, Giani AMaria, Zhang T, Lacko LA, Leng D, D Taylor L, Lee BN, Han Z, Jiao T, Huang Y, Zhao M, Liu X, Chong AChi Nok, Xue D, Meng Z, Xiang JZ, Pan C, Wang W, Naji A, Evans T, Liu J, Collins FS, Liu C, Chen S. ChemPerturb-seq screen identifies a small molecule cocktail enhancing human beta cell survival after subcutaneous transplantation. Cell Stem Cell. 2025;.

Homan EA, Gilani A, Rubio-Navarro A, Johnson MA, Schaepkens OM, Cortada E, de Lima RPereira, Stoll L, Lo JC. Complement 3a receptor 1 on macrophages and Kupffer cells is not required for the pathogenesis of metabolic dysfunction-associated steatotic liver disease. Elife. 2025;13.

Banks AS, Allison DB, Alquier T, Austad SN, Auwerx J, Ayala JE, Baur JA, Carobbio S, Churchill GA, Dall M, de Cabo R, Donato J, Dragano NRV, Elias CF, Ferrante AW, Finck BN, Galgani JE, Gerhart-Hines Z, Goodyear LJ, Grobe JL, Gupta RK, Habegger KM, Hartig SM, Hevener AL, Heymsfield SB, Holman CD, de Angelis MHrabě, James DE, Kazak L, Kim JBum, Klingenspor M, Kong X, Kooijman S, Lantier L, Lloyd KCKent, Lo JC, Lodhi IJ, MacLean PS, McGuinness OP, Medina-Gómez G, Mirmira RG, Morrison CD, Morton GJ, Müller TD, Ogawa Y, Pajuelo-Reguera D, Potthoff MJ, Qi N, Reitman ML, Rensen PCN, Rozman J, Rutkowsky JM, Sakamoto K, Scherer PE, Schwartz GJ, Sedlacek R, Selloum M, Shaikh SRaza, Chen S, Shulman GI, Škop V, Soukas AA, Speakman JR, Spiegelman BM, Steinberg GR, Svensson KJ, Thyfault JP, Tiganis T, Titchenell PM, Turner N, Velloso LA, Vidal-Puig A, Ward CS, Williams AS, Wolfrum C, Xu AW, Xu Y, Zierath JR. A consensus guide to preclinical indirect calorimetry experiments. Nat Metab. 2025;7(9):1765-1780.

Much C, Rajkumar SM, Chen L, Cohen JM, Gade AR, Pitt GS, Long Y. Distinct specificity and functions of PRC2 subcomplexes in human stem cells and cardiac differentiation. Mol Cell. 2025;85(16):3057-3073.e10.

Jin S, Yoon NAe, Wei M, Worgall T, Rubinelli L, Horvath TL, Min W, Diano N, Di Lorenzo A, Diano S. Endoplasmic reticulum Nogo drives AgRP neuronal activation and feeding behavior. Cell Metab. 2025;.

Ee L-S, Medina-Cano D, Goetzler E, Uyehara C, Schwarz C, Salataj E, Madhuranath S, Evans T, Hadjantonakis A-K, Apostolou E, Polyzos A, Vierbuchen T, Stadtfeld M. Enhancer remodeling by OTX2 directs specification and patterning of mammalian definitive endoderm. Dev Cell. 2025;.

Das LTanmoy, Malvezzi M, Gade A, Matsui M, McKay M, Wei EQ, Zelich MJ, Mazdisnian K, Kushner J, Chen B-X, DiStefano I, Roybal D, Yang L, Stoll L, Lo JC, Kalocsay M, Akar FG, Marx SO, Pitt GS. FGF13 regulates cardiomyocyte impulse propagation via Cx43 trafficking independent of voltage-gated sodium channels. bioRxiv. 2025;.

Han Y, Leng D, Zhang T, Ge J, Fang Y, Lu T, Dong X, Nair MS, de Silva N, Han Z, Jiao T, Huang Y, Zhao M, Saqi A, Hibshoosh H, Meng Z, Xiang JZ, Pan C, Sun Y, Ho DD, Evans T, Liu J, Yang L, Que J, Chen S. A Human Immuno-Lung Organoid Model to Study Macrophage-Mediated Lung Cell Senescence Upon SARS-CoV-2 Infection. Adv Sci (Weinh). 2025;12(36):e03932.

Lin S, Gade AR, Wang H-G, Niemeyer JE, Galante A, DiStefano I, Towers P, Nunez J, Matsui M, Schwartz TH, Rajadhyaksha A, Pitt GS. Interneuron FGF13 regulates seizure susceptibility via a sodium channel-independent mechanism. Elife. 2025;13.

Much C, Rajkumar SM, Chen L, Cohen JM, Gade AR, Pitt GS, Long Y. Macromolecular interactions dictate Polycomb-mediated epigenetic repression. bioRxiv. 2025;.

Gade AR, Malvezzi M, Das LTanmoy, Matsui M, Ma C-IJ, Mazdisnian K, Marx SO, Maxfield FR, Pitt GS. The NaV1.5 auxiliary subunit FGF13 modulates channels by regulating membrane cholesterol independent of channel binding. J Clin Invest. 2025;.

Lei CLok, Clark AP, Clerx M, Wei S, Bloothooft M, de Boer TP, Christini DJ, Krogh-Madsen T, Mirams GR. Resolving Artifacts in Voltage-Clamp Experiments with Computational Modeling: An Application to Fast Sodium Current Recordings. Adv Sci (Weinh). 2025;12(30):e00691.

Zhang F, Evans T. Stage-specific DNA methylation dynamics in mammalian heart development. Epigenomics. 2025;:1-13.

Rubinelli L, Manzo OLaura, Sungho J, Del Gaudio I, Bareja R, Marino A, Palikhe S, Di Mauro V, Bucci M, Falcone DJ, Elemento O, Ersoy B, Diano S, Sasset L, Di Lorenzo A. Suppression of endothelial ceramide de novo biosynthesis by Nogo-B contributes to cardiometabolic diseases. Nat Commun. 2025;16(1):1968.

Gilani A, Stoll L, Homan EA, Lo JC. Adipose Signals Regulating Distal Organ Health and Disease. Diabetes. 2024;73(2):169-177.

Ma L, Gilani A, Rubio-Navarro A, Cortada E, Li A, Reilly SM, Tang L, Lo JC. Adipsin and Adipocyte-derived C3aR1 Regulate Thermogenic Fat in a Sex-dependent Fashion. JCI Insight. 2024;.

Katchman AN, Zakharov SI, Bohnen MS, Jimenez ASanchez, Kushner JS, Yang L, Chen B-X, Nasari A, Liu G, Rabbani DE, Han J, Leu C-S, Pitt GS, Marx SO. Augmented Cardiac Inotropy by Phosphodiesterase Inhibition Requires Phosphorylation of Rad and Increased Calcium Current. Circulation. 2024;149(20):1617-1620.

Cortada E, Yao J, Xia Y, Dündar F, Zumbo P, Yang B, Rubio-Navarro A, Perder B, Qiu M, Pettinato AM, Homan EA, Stoll L, Betel D, Cao J, Lo JC. Cross-species single-cell RNA-seq analysis reveals disparate and conserved cardiac and extracardiac inflammatory responses upon heart injury. Commun Biol. 2024;7(1):1611.

Duca S, Xia Y, Elmagid LAbd, Bakis I, Qiu M, Cao Y, Guo Y, Eichenbaum JV, McCain ML, Kang J, Harrison MRM, Cao J. Differential vegfc expression dictates lymphatic response during zebrafish heart development and regeneration. Development. 2024;151(22).

Buth JE, Dyevich CE, Rubin A, Wang C, Gao L, Marks T, Harrison MRm, Kong JH, M Ross E, Novitch BG, Pearson CAlayne. Foxp1 suppresses cortical angiogenesis and attenuates HIF-1alpha signaling to promote neural progenitor cell maintenance. EMBO Rep. 2024;25(5):2202-2219.

Sam J, Torregroza I, Evans T. Gata6 functions in zebrafish endoderm to regulate late differentiating arterial pole cardiogenesis. Development. 2024;.