Publications

Naderi J, Johnson AKelsey, Thakkar H, Chandravanshi B, Ksiazek A, Anand A, Vincent V, Tran A, Kalimireddy A, Singh P, Sood A, Das A, Talbot CLamar, Distefano IA, J Maschek A, Cox J, Li Y, Summers SA, Atkinson DJ, Turapov T, Ratcliff JA, Fung J, Shabbir A, M Yassin S, Shiow S-AToh Ee, Holland WL, Pitt GS, Chaurasia B. Ceramide-induced FGF13 impairs systemic metabolic health. Cell Metab. 2025;.

Naderi J, Johnson AKelsey, Thakkar H, Chandravanshi B, Ksiazek A, Anand A, Vincent V, Tran A, Kalimireddy A, Singh P, Sood A, Das A, Talbot CLamar, Distefano IA, J Maschek A, Cox J, Li Y, Summers SA, Atkinson DJ, Turapov T, Ratcliff JA, Fung J, Shabbir A, M Yassin S, Shiow S-AToh Ee, Holland WL, Pitt GS, Chaurasia B. Ceramide-induced FGF13 impairs systemic metabolic health. Cell Metab. 2025;.

Naderi J, Johnson AKelsey, Thakkar H, Chandravanshi B, Ksiazek A, Anand A, Vincent V, Tran A, Kalimireddy A, Singh P, Sood A, Das A, Talbot CLamar, Distefano IA, J Maschek A, Cox J, Li Y, Summers SA, Atkinson DJ, Turapov T, Ratcliff JA, Fung J, Shabbir A, M Yassin S, Shiow S-AToh Ee, Holland WL, Pitt GS, Chaurasia B. Ceramide-induced FGF13 impairs systemic metabolic health. Cell Metab. 2025;.

Zhu J, Li Z, Xue D, Meng Z, Shao S, Pulecio J, Zhang G, Huangfu D, Evans T, Schultz PG, Chen S. A Chemical Epigenetic Probe to Capture the Site-Specific DNA-Binding Protein Complex. Res Sq. 2025;.

Zhu J, Li Z, Xue D, Meng Z, Shao S, Pulecio J, Zhang G, Huangfu D, Evans T, Chen S, Schultz PG. A chemical epigenetic tool to probe site-specific DNA-binding protein complexes. Proc Natl Acad Sci U S A. 2025;122(40):e2509021122.

J Vandana J, Zhu J, Giani AMaria, Zhang T, Lacko LA, Leng D, D Taylor L, Lee BN, Han Z, Jiao T, Huang Y, Zhao M, Liu X, Chong AChi Nok, Xue D, Meng Z, Xiang JZ, Pan C, Wang W, Naji A, Evans T, Liu J, Collins FS, Liu C, Chen S. ChemPerturb-seq screen identifies a small molecule cocktail enhancing human beta cell survival after subcutaneous transplantation. Cell Stem Cell. 2025;.

J Vandana J, Zhu J, Giani AMaria, Zhang T, Lacko LA, Leng D, D Taylor L, Lee BN, Han Z, Jiao T, Huang Y, Zhao M, Liu X, Chong AChi Nok, Xue D, Meng Z, Xiang JZ, Pan C, Wang W, Naji A, Evans T, Liu J, Collins FS, Liu C, Chen S. ChemPerturb-seq screen identifies a small molecule cocktail enhancing human beta cell survival after subcutaneous transplantation. Cell Stem Cell. 2025;.

J Vandana J, Zhu J, Giani AMaria, Zhang T, Lacko LA, Leng D, D Taylor L, Lee BN, Han Z, Jiao T, Huang Y, Zhao M, Liu X, Chong AChi Nok, Xue D, Meng Z, Xiang JZ, Pan C, Wang W, Naji A, Evans T, Liu J, Collins FS, Liu C, Chen S. ChemPerturb-seq screen identifies a small molecule cocktail enhancing human beta cell survival after subcutaneous transplantation. Cell Stem Cell. 2025;.

Homan EA, Gilani A, Rubio-Navarro A, Johnson MA, Schaepkens OM, Cortada E, de Lima RPereira, Stoll L, Lo JC. Complement 3a receptor 1 on macrophages and Kupffer cells is not required for the pathogenesis of metabolic dysfunction-associated steatotic liver disease. Elife. 2025;13.

Banks AS, Allison DB, Alquier T, Austad SN, Auwerx J, Ayala JE, Baur JA, Carobbio S, Churchill GA, Dall M, de Cabo R, Donato J, Dragano NRV, Elias CF, Ferrante AW, Finck BN, Galgani JE, Gerhart-Hines Z, Goodyear LJ, Grobe JL, Gupta RK, Habegger KM, Hartig SM, Hevener AL, Heymsfield SB, Holman CD, de Angelis MHrabě, James DE, Kazak L, Kim JBum, Klingenspor M, Kong X, Kooijman S, Lantier L, Lloyd KCKent, Lo JC, Lodhi IJ, MacLean PS, McGuinness OP, Medina-Gómez G, Mirmira RG, Morrison CD, Morton GJ, Müller TD, Ogawa Y, Pajuelo-Reguera D, Potthoff MJ, Qi N, Reitman ML, Rensen PCN, Rozman J, Rutkowsky JM, Sakamoto K, Scherer PE, Schwartz GJ, Sedlacek R, Selloum M, Shaikh SRaza, Chen S, Shulman GI, Škop V, Soukas AA, Speakman JR, Spiegelman BM, Steinberg GR, Svensson KJ, Thyfault JP, Tiganis T, Titchenell PM, Turner N, Velloso LA, Vidal-Puig A, Ward CS, Williams AS, Wolfrum C, Xu AW, Xu Y, Zierath JR. A consensus guide to preclinical indirect calorimetry experiments. Nat Metab. 2025;7(9):1765-1780.

Banks AS, Allison DB, Alquier T, Austad SN, Auwerx J, Ayala JE, Baur JA, Carobbio S, Churchill GA, Dall M, de Cabo R, Donato J, Dragano NRV, Elias CF, Ferrante AW, Finck BN, Galgani JE, Gerhart-Hines Z, Goodyear LJ, Grobe JL, Gupta RK, Habegger KM, Hartig SM, Hevener AL, Heymsfield SB, Holman CD, de Angelis MHrabě, James DE, Kazak L, Kim JBum, Klingenspor M, Kong X, Kooijman S, Lantier L, Lloyd KCKent, Lo JC, Lodhi IJ, MacLean PS, McGuinness OP, Medina-Gómez G, Mirmira RG, Morrison CD, Morton GJ, Müller TD, Ogawa Y, Pajuelo-Reguera D, Potthoff MJ, Qi N, Reitman ML, Rensen PCN, Rozman J, Rutkowsky JM, Sakamoto K, Scherer PE, Schwartz GJ, Sedlacek R, Selloum M, Shaikh SRaza, Chen S, Shulman GI, Škop V, Soukas AA, Speakman JR, Spiegelman BM, Steinberg GR, Svensson KJ, Thyfault JP, Tiganis T, Titchenell PM, Turner N, Velloso LA, Vidal-Puig A, Ward CS, Williams AS, Wolfrum C, Xu AW, Xu Y, Zierath JR. A consensus guide to preclinical indirect calorimetry experiments. Nat Metab. 2025;7(9):1765-1780.

Banks AS, Allison DB, Alquier T, Austad SN, Auwerx J, Ayala JE, Baur JA, Carobbio S, Churchill GA, Dall M, de Cabo R, Donato J, Dragano NRV, Elias CF, Ferrante AW, Finck BN, Galgani JE, Gerhart-Hines Z, Goodyear LJ, Grobe JL, Gupta RK, Habegger KM, Hartig SM, Hevener AL, Heymsfield SB, Holman CD, de Angelis MHrabě, James DE, Kazak L, Kim JBum, Klingenspor M, Kong X, Kooijman S, Lantier L, Lloyd KCKent, Lo JC, Lodhi IJ, MacLean PS, McGuinness OP, Medina-Gómez G, Mirmira RG, Morrison CD, Morton GJ, Müller TD, Ogawa Y, Pajuelo-Reguera D, Potthoff MJ, Qi N, Reitman ML, Rensen PCN, Rozman J, Rutkowsky JM, Sakamoto K, Scherer PE, Schwartz GJ, Sedlacek R, Selloum M, Shaikh SRaza, Chen S, Shulman GI, Škop V, Soukas AA, Speakman JR, Spiegelman BM, Steinberg GR, Svensson KJ, Thyfault JP, Tiganis T, Titchenell PM, Turner N, Velloso LA, Vidal-Puig A, Ward CS, Williams AS, Wolfrum C, Xu AW, Xu Y, Zierath JR. A consensus guide to preclinical indirect calorimetry experiments. Nat Metab. 2025;7(9):1765-1780.

Much C, Rajkumar SM, Chen L, Cohen JM, Gade AR, Pitt GS, Long Y. Distinct specificity and functions of PRC2 subcomplexes in human stem cells and cardiac differentiation. Mol Cell. 2025;85(16):3057-3073.e10.

Much C, Rajkumar SM, Chen L, Cohen JM, Gade AR, Pitt GS, Long Y. Distinct specificity and functions of PRC2 subcomplexes in human stem cells and cardiac differentiation. Mol Cell. 2025;85(16):3057-3073.e10.

Das LTanmoy, Malvezzi M, Gade A, Matsui M, McKay M, Wei EQ, Zelich MJ, Mazdisnian K, Kushner J, Chen B-X, DiStefano I, Roybal D, Yang L, Stoll L, Lo JC, Kalocsay M, Akar FG, Marx SO, Pitt GS. FGF13 regulates cardiomyocyte impulse propagation via Cx43 trafficking independent of voltage-gated sodium channels. bioRxiv. 2025;.

Han Y, Leng D, Zhang T, Ge J, Fang Y, Lu T, Dong X, Nair MS, de Silva N, Han Z, Jiao T, Huang Y, Zhao M, Saqi A, Hibshoosh H, Meng Z, Xiang JZ, Pan C, Sun Y, Ho DD, Evans T, Liu J, Yang L, Que J, Chen S. A Human Immuno-Lung Organoid Model to Study Macrophage-Mediated Lung Cell Senescence Upon SARS-CoV-2 Infection. Adv Sci (Weinh). 2025;12(36):e03932.

Much C, Rajkumar SM, Chen L, Cohen JM, Gade AR, Pitt GS, Long Y. Macromolecular interactions dictate Polycomb-mediated epigenetic repression. bioRxiv. 2025;.

Much C, Rajkumar SM, Chen L, Cohen JM, Gade AR, Pitt GS, Long Y. Macromolecular interactions dictate Polycomb-mediated epigenetic repression. bioRxiv. 2025;.

Lei CLok, Clark AP, Clerx M, Wei S, Bloothooft M, de Boer TP, Christini DJ, Krogh-Madsen T, Mirams GR. Resolving Artifacts in Voltage-Clamp Experiments with Computational Modeling: An Application to Fast Sodium Current Recordings. Adv Sci (Weinh). 2025;12(30):e00691.

Lei CLok, Clark AP, Clerx M, Wei S, Bloothooft M, de Boer TP, Christini DJ, Krogh-Madsen T, Mirams GR. Resolving Artifacts in Voltage-Clamp Experiments with Computational Modeling: An Application to Fast Sodium Current Recordings. Adv Sci (Weinh). 2025;12(30):e00691.

Lei CLok, Clark AP, Clerx M, Wei S, Bloothooft M, de Boer TP, Christini DJ, Krogh-Madsen T, Mirams GR. Resolving Artifacts in Voltage-Clamp Experiments with Computational Modeling: An Application to Fast Sodium Current Recordings. Adv Sci (Weinh). 2025;12(30):e00691.

Ma L, Gilani A, Rubio-Navarro A, Cortada E, Li A, Reilly SM, Tang L, Lo JC. Adipsin and Adipocyte-derived C3aR1 Regulate Thermogenic Fat in a Sex-dependent Fashion. JCI Insight. 2024;.

Katchman AN, Zakharov SI, Bohnen MS, Jimenez ASanchez, Kushner JS, Yang L, Chen B-X, Nasari A, Liu G, Rabbani DE, Han J, Leu C-S, Pitt GS, Marx SO. Augmented Cardiac Inotropy by Phosphodiesterase Inhibition Requires Phosphorylation of Rad and Increased Calcium Current. Circulation. 2024;149(20):1617-1620.

Cortada E, Yao J, Xia Y, Dündar F, Zumbo P, Yang B, Rubio-Navarro A, Perder B, Qiu M, Pettinato AM, Homan EA, Stoll L, Betel D, Cao J, Lo JC. Cross-species single-cell RNA-seq analysis reveals disparate and conserved cardiac and extracardiac inflammatory responses upon heart injury. Commun Biol. 2024;7(1):1611.

Cortada E, Yao J, Xia Y, Dündar F, Zumbo P, Yang B, Rubio-Navarro A, Perder B, Qiu M, Pettinato AM, Homan EA, Stoll L, Betel D, Cao J, Lo JC. Cross-species single-cell RNA-seq analysis reveals disparate and conserved cardiac and extracardiac inflammatory responses upon heart injury. Commun Biol. 2024;7(1):1611.